Set in Gunjo Gakuin, a school specialized for those deemed by the government to be unfit for society, CROSS†CHANNEL follows the story of eight members of the school's Broadcasting Club who have just returned from a disastrous field trip, which throws their club – and their friendships – into turmoil.

Upon returning to school, the students quickly discover that they are the only living people around. Completely alone and rife with tension, will the students manage to mend their broken friendships and complete their broadcasting antenna in order to reach out to other possible survivors of whatever mysterious calamity has befallen them? Or will they come apart at the seams?